Human-Hp Mismatch Boosts Stomach Cancer

Release Date:2014-06-30 08:28     Hits:2225

“A lot of people have H. pylori, but very few have bad outcomes. Is that due to the organism or the host?” says Martin Blaser, a microbiologist at New York University School of Medicine. “This paper provides evidence that the fit is important. It’s a very nice advance.”

The study led by Pelayo Correa and Scott Williams at Vanderbilt University Medical Center in Nashville, Tennessee, has shown that this mismatch can turn a normally benign infection into a potentially carcinogenic one. When analysed together, the genomes of hosts and microbes give a better prediction of the risk of disease than when considered alone, the team found. Their results were published in Proceedings of the National Academy of Sciences.

For original article, please see:
http://www.nature.com/news/human-microbe-mismatch-boosts-risk-of-stomach-cancer-1.14501.

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